UPitt TriState SenNet TMC Donor acceptance criteria
John Sembrat, Alison Morris, Melanie Königshoff, Oliver Eickelberg
Published: 2022-12-20 DOI: 10.17504/protocols.io.3byl4jwr2lo5/v1
Abstract
This document outlines the required criteria for donor inclusion of lung and heart specimens in the TriState SenNet TMC Biospecimen Core at the University of Pittsburgh, as part of the Cellular Senescence Network Program (SenNet). The study intends to be as inclusive as possible of race and ethnicity, dependent only on the consent for donor tissue for research. Disease known at the time of donation or later identified during the research will not necessarily exclude the sample from the research program.
Steps
Inclusion Criteria
1.
Inclusion Criteria:
- Age: Adulthood -Young through middle age and senior years (approx. 18 to >95 years)
- All sex, gender, race, ethnicity are eligible
- Known state of health and diagnoses
Exclusion Criteria
2.
Exclusion Criteria:
- Unknown time of death
- Prolonged Warm Ischemic Time (more than 2h)
- Prolonged Cold Ischemic Time (more than 18h)
- Known diseases including congenital anomaly or inborn error unsuitable for SenNet research
- Infection with high-level organisms representing risk in processing and shipment
