Hyperpolarized water as universal sensitivity booster in biomolecular NMR

Christian Hilty, Dennis Kurzbach, Lucio Frydman

Published: 2022-05-10 DOI: 10.1038/s41596-022-00693-8

NMR spectroscopy

Hyperpolarized water

Biomolecular dynamics

Signal amplification

Protein-RNA interactions

AI 解读

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Hyperpolarized water as universal sensitivity booster in biomolecular NMR

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NMR spectroscopy is the only method to access the structural dynamics of biomolecules at high (atomistic) resolution in their native solution state. However, this method’s low sensitivity has two important consequences: (i) typically experiments h
Introduction
Materials
Procedure
Troubleshooting
Timing
Anticipated results
References
ACKNOWLEDGMENTS

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Hyperpolarized water as universal sensitivity booster in biomolecular NMR

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