The efficacy of radical antegrade modular pancreatosplenectomy: a systematic review and meta-analysis protocol

Jun Watanabe, Kazuma Rifu, Hideki Sasanuma, Kazuhiko Kotani, Naohiro Sata

Published: 2021-08-19 DOI: 10.17504/protocols.io.bxhfpj3n

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Abstract

Background: Previous systematic reviews showed that radical antegrade modular pancreatosplenectomy (RAMPS) had good outcomes including the prognosis. However, recent large studies have shown opposite results, which is open to augment on RAMPS. The present study will aim to update the evidence on clinical outcomes of patients with left-sided pancreatic cancer underwent RAMPS compared to standard approach.

Methods: Electronic databases and registries will be searched to perform random-effect meta-analysis. Methodological quality will be assessed using the Grading of Recommendations, Assessment, Development, and Evaluation approach. The protocol will be registered (https://www.protocols.io/).

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