SenNet Case Selection Protocol | JHU TMC

Kyu Sang Han, Pei-Hsun Wu, Sashank Reddy, Denis Wirtz, Joel Sunshine, Fan Wu

Published: 2024-04-19 DOI: 10.17504/protocols.io.q26g71z1kgwz/v2

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Abstract

Inclusion

Age below 30 or above 50.

English Speaking.

Able to provide consent.

Resected pancreas tissue.

Clear and normal

structured islets of Langerhans, acinus, and ducts from H&E.

Exclusion

Large region of squamous

metaplasia or PanIN.

Abnormal or missing hematoxylin

nucleus stain.

Strong personal history of

diabetes or pancreatitis.

Large area percentage of

stromal cells.

Steps

Disclaimer

1.

Patient samples will be obtained from distal pancreatectomy, splenectomy, and cholecystectomy. No other procedures or follow-up is needed for research purposes.

Inclusion

2.

Age below 30 or above 50.

English Speaking.

Able to provide consent.

Resected pancreas tissue.

Clear and normal structured islets of Langerhans, acinus, and ducts from

H&E.

Exclusion

3.

Large region of squamous metaplasia or PanIN.

Abnormal or missing hematoxylin nucleus stain.

Strong personal history of diabetes or pancreatitis.

Large area percentage of stromal cells.

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