Reconstructing phylogenetic trees from genome-wide somatic mutations in clonal samples

Tim H. H. Coorens, Inigo Martincorena, Peter J. Campbell, Michael Spencer Chapman, Nicholas Williams, Michael R. Stratton, Jyoti Nangalia

Published: 2024-02-23 DOI: 10.1038/s41596-024-00962-8

somatic mutations

phylogenetic tree reconstruction

clonal samples

Sequoia pipeline

single-cell DNA sequencing

AI 解读

Supplementary information

Reporting Summary

Genetic manipulation and immortalized culture of ex vivo primary human germinal center B cells

The cell-line-derived subcutaneous tumor model in preclinical cancer research

Subcellular patch-clamp techniques for single-bouton stimulation and simultaneous pre- and postsynaptic recording at cortical synapses

NovoSpaRc: flexible spatial reconstruction of single-cell gene expression with optimal transport

Genome-wide pooled CRISPR screening in neurospheres

High-throughput cultivation and identification of bacteria from the plant root microbiota

Viral crosslinking and solid-phase purification enables discovery of ribonucleoprotein complexes on incoming RNA virus genomes

Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility

Addendum: Micro-CT acquisition and image processing to track and characterize pulmonary nodules in mice

Multiplexed single-cell proteomics using SCoPE2

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Supplementary information

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Reconstructing phylogenetic trees from genome-wide somatic mutations in clonal samples

Supplementary information

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