Nest Building Test
Ted Dawson, Hanseok Ko, Valina L. Dawson
Published: 2024-02-08 DOI: 10.17504/protocols.io.e6nvwdr42lmk/v1
Disclaimer
The protocols.io team notes that research involving animals and humans must be conducted according to internationally-accepted standards and should always have prior approval from an Institutional Ethics Committee or Board.
Abstract
Used to assess nigrostriatal sensorimotor function in mice. Based on the Deacon 2006 protocol.
Steps
1.
Place 2.5 g nestlet into feeder of each cage.
2.
Individually house mice must then pull the cotton nestlet from the feeder by rearing and useing complext fine motor skills.
3.
Scores based on the amount of unused nestlet material were determined 16 hours after the nestlet was placed. Further details on scoring can be seen in Deacon 2006.
