Multiplexed single-cell proteomics using SCoPE2

Andrew Leduc, Nikolai Slavov, Aleksandra A. Petelski, Edward Emmott, R. Gray Huffman, Harrison Specht, David H. Perlman

Published: 2021-10-28 DOI: 10.1038/s41596-021-00616-z

Mass spectrometry

Single-cell proteomics

SCoPE2

Isobaric labeling

Multiplexed analysis

AI 解读

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Multiplexed single-cell proteomics using SCoPE2

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Many biological systems are composed of diverse single cells. This diversity necessitates functional and molecular single-cell analysis. Single-cell protein analysis has long relied on affinity reagents, but emerging mass-spectrometry methods (either labe
Introduction
Materials
Procedure
Troubleshooting
Timings
- Preparatory work
- Single-cell work
Anticipated results
- References
- References
References
ACKNOWLEDGMENTS
ACKNOWLEDGMENTS

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Multiplexed single-cell proteomics using SCoPE2

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