Human Knee Tissue Procurement, Resection and Multimodal Analyses 

Informed written consent was obtained from all tissue donors and the study was approved by the Scripps Institutional Review Board (IRB# 22-8069).

This protocol describes the procurement of entire human knee joints, resection of joint tissues and allocation for multimodal analyses. The protocol is focused on entire knees that are recovered by Organ Procurement Organizations and parts of the protocol are also applicable for human joint tissues that are removed during surgery on the knee or other joints. For entire knees, samples of all joint tissues are resected to allow analysis of ‘the knee as an organ’. 

HUMAN KNEE TISSUE PROCUREMENT, RESECTION AND PROCESSING FOR MULTIMODAL ANALYSES.pdf