在生信分析过程中，经常会遇到各种评价标准，比如OS、DFS、RFS（DFS=RFS）。但是这个RFS全拼是 Relapse Free Survival 这个Relapse 和Recurrence ，中文都是复发的意思，但是确实不一样的，为了更好的理解RFS这个概念。我们搜集了歪果仁整理的5R的英文定义。希望对大家理解概念有所帮助。

以下内容来自psychologytoday

https://www.psychologytoday.com/us/blog/

ResponseThe first objective in the treatment of your depression is to get you to a response level. Response is clinically defined as an improvement from the initial onset of your illness. The goal herein would be to report less depressive symptoms. It doesn't matter if you're involved in psychotherapyand/or pharmacotherapy. What does matter is that you experience feeling better. Getting to a response level will be easy for some, moderate for others, and harder for those with treatment resistant depression. When it comes to a response, don't compare yourself with another person's experience. Instead, focus on your biology and biography to set realistic goals.RemissionThe second goal in treating your depression is to bring you to a full state of remission. Remissionis clinically defined as the experience of being symptom-free from illness. This differs from response in that you not only report an improvement from when you started treatment, but also describe the presence of well-being, optimism, self-confidence and a return to a healthy state of functioning. It is important to follow your treatment plan so you can achieve a full state of remission. Not doing so can lead to a partial remission - an experience of significant improvement where mild symptoms still exist. It is VERY IMPORTANT to know that if you're still experiencing depressive symptoms, you have not reached a full remission. Partial remission signals the need to continue with your treatment for depression. This is where most children and adults with unipolar or bipolar disorderslose their way. They stop taking their medication or interrupt psychotherapy because they "feel better"... but in actuality, they haven't achieved a full remission.RecoveryRecovery is clinically defined as the absence of symptoms for at least 4 months following the onset of remission. Recovery presents with periods of improvement and growth as well as with setbacks and stumbling blocks. So, essentially, you'll have good days and you'll have bad days. And yes, the human experience is one where you'll feel depressed, fatigued and hopeless from time to time. It's important to monitor yourself by assessing your physical and emotional experiences with the tools you've learned in psychotherapy. It is also imperative to keep up with your medication if that's part of your treatment plan. Research states that over 50% of children and adults who have a mood disorder will not achieve recovery because they don't tend to this stage of treatment, which is sometimes called the continuation phase of treatment.Relapse and RecurrenceRelapse and Recurrence are terms commonly used to describe a return of depressive symptoms. In truth, though, they are distinctly different experiences. Relapse is defined as a full return of depressive symptoms once remission has occurred - but before recovery has taken hold. Recurrence refers to another depressive episode after recovery has been attained.欢迎关注TCGA | 小工具 | 数据库 |组装| 注释 |   基因家族  |  Pvalue基因预测  |bestorf |  sci | NAR | 在线工具 | 生存分析 | 热图 生信不死 | 初学者 | circRNA | 一箭画心| 十二生肖 | circos 舞台|基因组 | 黄金测序 | 套路 | 杂谈组装 |  进化 | 测序简史